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Effects of microgravity on osteoblast mitochondria: a proteomic and metabolomics profile

The response of human primary osteoblasts exposed to simulated microgravity has been investigated and analysis of metabolomic and proteomic profiles demonstrated a prominent dysregulation of mitochondrion homeostasis. Gravitational unloading treatment induced a decrease in mitochondrial proteins, ma...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Michaletti, Anna, Gioia, Magda, Tarantino, Umberto, Zolla, Lello
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5684136/
https://ncbi.nlm.nih.gov/pubmed/29133864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-15612-1
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