Actin Microfilament Mediates Osteoblast Cbfa1 Responsiveness to BMP2 under Simulated Microgravity

Microgravity decreases osteoblastic activity, induces actin microfilament disruption and inhibits the responsiveness of osteoblast to cytokines, but the mechanisms remains enigmatic. The F-actin cytoskeleton has previously been implicated in manifold changes of cell shape, function and signaling obs...

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Bibliografiska uppgifter
Huvudupphovsmän: Dai, Zhongquan, Wu, Feng, Chen, Jian, Xu, Hongjie, Wang, Honghui, Guo, Feima, Tan, Yingjun, Ding, Bai, Wang, Jinfu, Wan, Yumin, Li, Yinghui
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2013
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3651164/
https://ncbi.nlm.nih.gov/pubmed/23675497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0063661
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