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Microgravity induces inhibition of osteoblastic differentiation and mineralization through abrogating primary cilia

It is well documented that microgravity in space environment leads to bone loss in astronauts. These physiological changes have also been validated by human and animal studies and modeled in cell-based analogs. However, the underlying mechanisms are elusive. In the current study, we identified a nov...

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Foilsithe in:Sci Rep
Main Authors: Shi, Wengui, Xie, Yanfang, He, Jinpeng, Zhou, Jian, Gao, Yuhai, Wei, Wenjun, Ding, Nan, Ma, Huiping, Xian, Cory J., Chen, Keming, Wang, Jufang
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group UK 2017
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Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5431935/
https://ncbi.nlm.nih.gov/pubmed/28500304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-02049-9
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