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Microgravity induces inhibition of osteoblastic differentiation and mineralization through abrogating primary cilia

It is well documented that microgravity in space environment leads to bone loss in astronauts. These physiological changes have also been validated by human and animal studies and modeled in cell-based analogs. However, the underlying mechanisms are elusive. In the current study, we identified a nov...

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Publicat a:Sci Rep
Autors principals: Shi, Wengui, Xie, Yanfang, He, Jinpeng, Zhou, Jian, Gao, Yuhai, Wei, Wenjun, Ding, Nan, Ma, Huiping, Xian, Cory J., Chen, Keming, Wang, Jufang
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5431935/
https://ncbi.nlm.nih.gov/pubmed/28500304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-02049-9
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