Poor prognosis in cholangiocarcinoma patients with low FBXW7 expression is improved by chemotherapy

The tumor suppressor FBXW7 has been demonstrated to degrade several oncoproteins, including c-Myc. Although low FBXW7 expression levels are suggested to be a poor prognostic factor in a number of types of solid tumor, the role of FBXW7 in chemosensitivity is controversial. The purpose of the present...

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Détails bibliographiques
Publié dans:Oncol Lett
Auteurs principaux: Ishii, Norihiro, Araki, Kenichiro, Yokobori, Takehiko, Watanabe, Akira, Tsukagoshi, Mariko, Kubo, Norio, Suzuki, Hideki, Saito, Fumiyoshi, Altan, Bolag, Hosouchi, Yasuo, Shirabe, Ken, Kuwano, Hiroyuki
Format: Artigo
Langue:Inglês
Publié: D.A. Spandidos 2017
Sujets:
Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5431321/
https://ncbi.nlm.nih.gov/pubmed/28521468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.5946
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