HIF-1α acts as a molecular target for simvastatin cytotoxicity in B16.F10 melanoma cells cultured under chemically induced hypoxia

Our previous studies reported that one of the main mechanisms of the antitumor activity of simvastatin (SIM) in B16.F10 murine melanoma cells was associated with strong suppression of the constitutive cell production of the α subunit of the heterodimeric transcription factor hypoxia-inducible factor...

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Xehetasun bibliografikoak
Argitaratua izan da:Oncol Lett
Egile Nagusiak: Licarete, Emilia, Sesarman, Alina, Rauca, Valentin Florian, Luput, Lavinia, Patras, Laura, Banciu, Manuela
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: D.A. Spandidos 2017
Gaiak:
Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5431316/
https://ncbi.nlm.nih.gov/pubmed/28521491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.5928
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