Adult murine cardiomyocytes exhibit regenerative activity with cell cycle reentry through STAT3 in the healing process of myocarditis

Mammalian cardiomyocytes substantially lose proliferative capacity immediately after birth, limiting adult heart regeneration after injury. However, clinical myocarditis appears to be self-limiting with tissue-reparative properties. Here, we investigated the molecular mechanisms underlying the recov...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Miyawaki, Akimitsu, Obana, Masanori, Mitsuhara, Yusuke, Orimoto, Aya, Nakayasu, Yusuke, Yamashita, Tomomi, Fukada, So-ichiro, Maeda, Makiko, Nakayama, Hiroyuki, Fujio, Yasushi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5431117/
https://ncbi.nlm.nih.gov/pubmed/28469272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-01426-8
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