Adult murine cardiomyocytes exhibit regenerative activity with cell cycle reentry through STAT3 in the healing process of myocarditis

Mammalian cardiomyocytes substantially lose proliferative capacity immediately after birth, limiting adult heart regeneration after injury. However, clinical myocarditis appears to be self-limiting with tissue-reparative properties. Here, we investigated the molecular mechanisms underlying the recov...

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Miyawaki, Akimitsu, Obana, Masanori, Mitsuhara, Yusuke, Orimoto, Aya, Nakayasu, Yusuke, Yamashita, Tomomi, Fukada, So-ichiro, Maeda, Makiko, Nakayama, Hiroyuki, Fujio, Yasushi
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2017
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5431117/
https://ncbi.nlm.nih.gov/pubmed/28469272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-01426-8
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