Adult murine cardiomyocytes exhibit regenerative activity with cell cycle reentry through STAT3 in the healing process of myocarditis

Mammalian cardiomyocytes substantially lose proliferative capacity immediately after birth, limiting adult heart regeneration after injury. However, clinical myocarditis appears to be self-limiting with tissue-reparative properties. Here, we investigated the molecular mechanisms underlying the recov...

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Vydáno v:Sci Rep
Hlavní autoři: Miyawaki, Akimitsu, Obana, Masanori, Mitsuhara, Yusuke, Orimoto, Aya, Nakayasu, Yusuke, Yamashita, Tomomi, Fukada, So-ichiro, Maeda, Makiko, Nakayama, Hiroyuki, Fujio, Yasushi
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5431117/
https://ncbi.nlm.nih.gov/pubmed/28469272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-01426-8
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