Xanthine oxidase inhibition by febuxostat attenuates stress-induced hyperuricemia, glucose dysmetabolism, and prothrombotic state in mice

Chronic stress is closely linked to the metabolic syndrome, diabetes, hyperuricemia and thromboembolism, but the mechanisms remain elusive. We reported recently that stress targets visceral adipose tissue (VAT), inducing lipolysis, low-grade inflammation with production of inflammatory adipokines, m...

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發表在:Sci Rep
Main Authors: Yisireyili, Maimaiti, Hayashi, Motoharu, Wu, Hongxian, Uchida, Yasuhiro, Yamamoto, Koji, Kikuchi, Ryosuke, Shoaib Hamrah, Mohammad, Nakayama, Takayuki, Wu Cheng, Xian, Matsushita, Tadashi, Nakamura, Shigeo, Niwa, Toshimitsu, Murohara, Toyoaki, Takeshita, Kyosuke
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2017
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5430858/
https://ncbi.nlm.nih.gov/pubmed/28455534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-01366-3
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