Xanthine oxidase inhibition by febuxostat attenuates stress-induced hyperuricemia, glucose dysmetabolism, and prothrombotic state in mice

Chronic stress is closely linked to the metabolic syndrome, diabetes, hyperuricemia and thromboembolism, but the mechanisms remain elusive. We reported recently that stress targets visceral adipose tissue (VAT), inducing lipolysis, low-grade inflammation with production of inflammatory adipokines, m...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Yisireyili, Maimaiti, Hayashi, Motoharu, Wu, Hongxian, Uchida, Yasuhiro, Yamamoto, Koji, Kikuchi, Ryosuke, Shoaib Hamrah, Mohammad, Nakayama, Takayuki, Wu Cheng, Xian, Matsushita, Tadashi, Nakamura, Shigeo, Niwa, Toshimitsu, Murohara, Toyoaki, Takeshita, Kyosuke
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2017
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5430858/
https://ncbi.nlm.nih.gov/pubmed/28455534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-01366-3
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