Melatonin and its metabolites protect human melanocytes against UVB-induced damage: Involvement of NRF2-mediated pathways

Ultraviolet light (UV) is an inducer of reactive oxygen species (ROS) as well as 6-4-photoproducts and cyclobutane pyrimidine dimers (CPD) in the skin, which further cause damage to the skin cells. Irradiation of cultured human melanocytes with UVB stimulated ROS production, which was reduced in cel...

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Publicat a:Sci Rep
Autors principals: Janjetovic, Zorica, Jarrett, Stuart G., Lee, Elizabeth F., Duprey, Cory, Reiter, Russel J., Slominski, Andrzej T.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5430855/
https://ncbi.nlm.nih.gov/pubmed/28455491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-01305-2
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