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Melatonin and its metabolites protect human melanocytes against UVB-induced damage: Involvement of NRF2-mediated pathways

Ultraviolet light (UV) is an inducer of reactive oxygen species (ROS) as well as 6-4-photoproducts and cyclobutane pyrimidine dimers (CPD) in the skin, which further cause damage to the skin cells. Irradiation of cultured human melanocytes with UVB stimulated ROS production, which was reduced in cel...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Janjetovic, Zorica, Jarrett, Stuart G., Lee, Elizabeth F., Duprey, Cory, Reiter, Russel J., Slominski, Andrzej T.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5430855/
https://ncbi.nlm.nih.gov/pubmed/28455491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-01305-2
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