Double-stranded DNA induces a prothrombotic phenotype in the vascular endothelium

Double-stranded DNA (dsDNA) constitutes a potent activator of innate immunity, given its ability to bind intracellular pattern recognition receptors during viral infections or sterile tissue damage. While effects of dsDNA in immune cells have been extensively studied, dsDNA signalling and its pathop...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Gaitzsch, Erik, Czermak, Thomas, Ribeiro, Andrea, Heun, Yvonn, Bohmer, Monica, Merkle, Monika, Mannell, Hanna, Schulz, Christian, Wörnle, Markus, Pircher, Joachim
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5430798/
https://ncbi.nlm.nih.gov/pubmed/28442771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-01148-x
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