Microspectrofluorimetry to dissect the permeation of ceftazidime in Gram-negative bacteria

A main challenge in chemotherapy is to determine the in cellulo parameters modulating the drug concentration required for therapeutic action. It is absolutely urgent to understand membrane permeation and intracellular concentration of antibiotics in clinical isolates: passing the membrane barrier to...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Allam, Anas, Maigre, Laure, Vergalli, Julia, Dumont, Estelle, Cinquin, Bertrand, Alves de Sousa, Rodolphe, Pajovic, Jelena, Pinet, Elizabeth, Smith, Nikaia, Herbeuval, Jean-Philippe, Réfrégiers, Matthieu, Artaud, Isabelle, Pagès, Jean-Marie
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2017
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5430551/
https://ncbi.nlm.nih.gov/pubmed/28428543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00945-8
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