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Microspectrofluorimetry to dissect the permeation of ceftazidime in Gram-negative bacteria

A main challenge in chemotherapy is to determine the in cellulo parameters modulating the drug concentration required for therapeutic action. It is absolutely urgent to understand membrane permeation and intracellular concentration of antibiotics in clinical isolates: passing the membrane barrier to...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Allam, Anas, Maigre, Laure, Vergalli, Julia, Dumont, Estelle, Cinquin, Bertrand, Alves de Sousa, Rodolphe, Pajovic, Jelena, Pinet, Elizabeth, Smith, Nikaia, Herbeuval, Jean-Philippe, Réfrégiers, Matthieu, Artaud, Isabelle, Pagès, Jean-Marie
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5430551/
https://ncbi.nlm.nih.gov/pubmed/28428543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00945-8
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