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Mechanistic aspects of maltotriose-conjugate translocation to the Gram-negative bacteria cytoplasm

Small molecule accumulation in Gram-negative bacteria is a key challenge to discover novel antibiotics, because of their two membranes and efflux pumps expelling toxic molecules. An approach to overcome this challenge is to hijack uptake pathways so that bacterial transporters shuttle the antibiotic...

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Detalhes bibliográficos
Publicado no:Life Sci Alliance
Main Authors: Dumont, Estelle, Vergalli, Julia, Pajovic, Jelena, Bhamidimarri, Satya P, Morante, Koldo, Wang, Jiajun, Lubriks, Dmitrijs, Suna, Edgars, Stavenger, Robert A, Winterhalter, Mathias, Réfrégiers, Matthieu, Pagès, Jean-Marie
Formato: Artigo
Idioma:Inglês
Publicado em: Life Science Alliance LLC 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6311466/
https://ncbi.nlm.nih.gov/pubmed/30620010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.201800242
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