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Ketogenic diet attenuates hepatopathy in mouse model of respiratory chain complex III deficiency caused by a Bcs1l mutation

Mitochondrial disorders are among the most prevalent inborn errors of metabolism but largely lack treatments and have poor outcomes. High-fat, low-carbohydrate ketogenic diets (KDs) have shown beneficial effects in mouse models of mitochondrial myopathies, with induction of mitochondrial biogenesis...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Purhonen, Janne, Rajendran, Jayasimman, Mörgelin, Matthias, Uusi-Rauva, Kristiina, Katayama, Shintaro, Krjutskov, Kaarel, Einarsdottir, Elisabet, Velagapudi, Vidya, Kere, Juha, Jauhiainen, Matti, Fellman, Vineta, Kallijärvi, Jukka
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5430426/
https://ncbi.nlm.nih.gov/pubmed/28424480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-01109-4
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