Recombinant Slit2 Reduces Surgical Brain Injury Induced Blood Brain Barrier Disruption via Robo4 Dependent Rac1 Activation in a Rodent Model

Brain tissue surrounding surgical resection site can be injured inadvertently due to procedures such as incision, retractor stretch, and electrocauterization when performing neurosurgical procedures, which is termed as surgical brain injury (SBI). Blood brain barrier (BBB) disruption due to SBI can...

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Pubblicato in:Sci Rep
Autori principali: Sherchan, Prativa, Huang, Lei, Akyol, Onat, Reis, Cesar, Tang, Jiping, Zhang, John H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5429690/
https://ncbi.nlm.nih.gov/pubmed/28389649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00827-z
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