G-protein coupled receptor 15 mediates angiogenesis and cytoprotective function of thrombomodulin

Thrombomodulin (TM) stimulates angiogenesis and protects vascular endothelial cells (ECs) via its fifth epidermal growth factor-like region (TME5); however, the cell surface receptor that mediates the pro-survival signaling activated by TM has remained unknown. We applied pull-down assay followed by...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Pan, Bin, Wang, Xiangmin, Nishioka, Chie, Honda, Goichi, Yokoyama, Akihito, Zeng, Lingyu, Xu, Kailin, Ikezoe, Takayuki
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5429650/
https://ncbi.nlm.nih.gov/pubmed/28386128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00781-w
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