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DHMEQ, a novel nuclear factor-κB inhibitor, induces selective depletion of alloreactive or phytohaemagglutinin-stimulated peripheral blood mononuclear cells, decreases production of T helper type 1 cytokines, and blocks maturation of dendritic cells

Dehydroxymethylepoxyquinomicin (DHMEQ), a novel nuclear factor κB (NF-κB) inhibitor, has been shown to be active against variety types of solid tumours as well as haematological malignant cells. This study explored the anti-inflammatory effects of DHMEQ in vitro. DHMEQ inhibited the proliferation of...

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書誌詳細
主要な著者: Nishioka, Chie, Ikezoe, Takayuki, Jing, Yang, Umezawa, Kazuo, Yokoyama, Akihito
フォーマット: Artigo
言語:Inglês
出版事項: Blackwell Science Inc 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2566624/
https://ncbi.nlm.nih.gov/pubmed/18217958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2007.02755.x
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