Cytoprotective and pro-angiogenic functions of thrombomodulin are preserved in the C loop of the fifth epidermal growth factor-like domain

We previously found that the fifth epidermal growth factor-like domain of thrombomodulin (TME5) exerts cytoprotective and pro-angiogenic functions via G-protein coupled receptor 15 (GPR15). TME5 is comprised of three S-S bonds that divide it into three loops: A (TME5A), B (TME5B), and C (TME5C). Her...

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Détails bibliographiques
Publié dans:Haematologica
Auteurs principaux: Wang, Xiangmin, Pan, Bin, Honda, Goichi, Wang, Xintao, Hashimoto, Yuko, Ohkawara, Hiroshi, Xu, Kailin, Zeng, Lingyu, Ikezoe, Takayuki
Format: Artigo
Langue:Inglês
Publié: Ferrata Storti Foundation 2018
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6165823/
https://ncbi.nlm.nih.gov/pubmed/29903766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2017.184481
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