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Loss of p27(kip1) increases genomic instability and induces radio-resistance in luminal breast cancer cells
Genomic instability represents a typical feature of aggressive cancers. Normal cells have evolved intricate responses to preserve genomic integrity in response to stress, such as DNA damage induced by γ-irradiation. Cyclin-dependent kinases (CDKs) take crucial part to these safeguard mechanisms, but...
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| Published in: | Sci Rep |
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| Main Authors: | , , , , , , , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Nature Publishing Group UK
2017
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5429596/ https://ncbi.nlm.nih.gov/pubmed/28377607 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00734-3 |
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