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Acidic cellular microenvironment modifies carcinogen-induced DNA damage and repair
Chronic inflammation creates an acidic microenvironment, which plays an important role in cancer development. To investigate how low pH changes the cellular response to the carcinogen benzo[a]pyrene (B[a]P), we incubated human pulmonary epithelial cells (A549 and BEAS-2B) with nontoxic doses of B[a]...
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| Publicado no: | Arch Toxicol |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Berlin Heidelberg
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5429366/ https://ncbi.nlm.nih.gov/pubmed/28005143 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-016-1907-4 |
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