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Acidic cellular microenvironment modifies carcinogen-induced DNA damage and repair
Chronic inflammation creates an acidic microenvironment, which plays an important role in cancer development. To investigate how low pH changes the cellular response to the carcinogen benzo[a]pyrene (B[a]P), we incubated human pulmonary epithelial cells (A549 and BEAS-2B) with nontoxic doses of B[a]...
Guardat en:
| Publicat a: | Arch Toxicol |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Springer Berlin Heidelberg
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5429366/ https://ncbi.nlm.nih.gov/pubmed/28005143 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-016-1907-4 |
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