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DTNI: a novel toxicogenomics data analysis tool for identifying the molecular mechanisms underlying the adverse effects of toxic compounds

Unravelling gene regulatory networks (GRNs) influenced by chemicals is a major challenge in systems toxicology. Because toxicant-induced GRNs evolve over time and dose, the analysis of global gene expression data measured at multiple time points and doses will provide insight in the adverse effects...

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Publicat a:Arch Toxicol
Autors principals: Hendrickx, Diana M., Souza, Terezinha, Jennen, Danyel G. J., Kleinjans, Jos C. S.
Format: Artigo
Idioma:Inglês
Publicat: Springer Berlin Heidelberg 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5429357/
https://ncbi.nlm.nih.gov/pubmed/28032149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-016-1922-5
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