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WDR23 regulates NRF2 independently of KEAP1
Cellular adaptation to stress is essential to ensure organismal survival. NRF2/NFE2L2 is a key determinant of xenobiotic stress responses, and loss of negative regulation by the KEAP1-CUL3 proteasome system is implicated in several chemo- and radiation-resistant cancers. Advantageously using C. eleg...
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| Vydáno v: | PLoS Genet |
|---|---|
| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Public Library of Science
2017
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5428976/ https://ncbi.nlm.nih.gov/pubmed/28453520 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006762 |
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