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Identification of small molecule inhibitors of Interleukin-18

Interleukin-18 (IL-18) is a pleiotropic pro-inflammatory cytokine belonging to the IL-1 superfamily. IL-18 plays an important role in host innate and adaptive immune defense but its aberrant activities are also associated with inflammatory diseases such as rheumatoid arthritis and Crohn's disea...

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書目詳細資料
發表在:Sci Rep
Main Authors: Krumm, Brian, Meng, Xiangzhi, Xiang, Yan, Deng, Junpeng
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5428663/
https://ncbi.nlm.nih.gov/pubmed/28352119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00532-x
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