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A Unique Bivalent Binding and Inhibition Mechanism by the Yatapoxvirus Interleukin 18 Binding Protein

Interleukin 18 (IL18) is a cytokine that plays an important role in inflammation as well as host defense against microbes. Mammals encode a soluble inhibitor of IL18 termed IL18 binding protein (IL18BP) that modulates IL18 activity through a negative feedback mechanism. Many poxviruses encode homolo...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Krumm, Brian, Meng, Xiangzhi, Wang, Zhixin, Xiang, Yan, Deng, Junpeng
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3426546/
https://ncbi.nlm.nih.gov/pubmed/22927815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002876
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