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Structural basis for antagonism of human interleukin 18 by poxvirus interleukin 18-binding protein
Human interleukin-18 (hIL-18) is a cytokine that plays an important role in inflammation and host defense against microbes. Its activity is regulated in vivo by a naturally occurring antagonist, the human IL-18-binding protein (IL-18BP). Functional homologs of human IL-18BP are encoded by all orthop...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2634891/ https://ncbi.nlm.nih.gov/pubmed/19104048 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0809086106 |
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