The G2A receptor (GPR132) contributes to oxaliplatin-induced mechanical pain hypersensitivity

Chemotherapy-induced peripheral neuropathic pain (CIPN) is a common and severe debilitating side effect of many widely used cytostatics. However, there is no approved pharmacological treatment for CIPN available. Among other substances, oxaliplatin causes CIPN in up to 80% of treated patients. Here,...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Hohmann, Stephan W., Angioni, Carlo, Tunaru, Sorin, Lee, Seungkyu, Woolf, Clifford J., Offermanns, Stefan, Geisslinger, Gerd, Scholich, Klaus, Sisignano, Marco
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5428564/
https://ncbi.nlm.nih.gov/pubmed/28348394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00591-0
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