The G2A receptor (GPR132) contributes to oxaliplatin-induced mechanical pain hypersensitivity

Chemotherapy-induced peripheral neuropathic pain (CIPN) is a common and severe debilitating side effect of many widely used cytostatics. However, there is no approved pharmacological treatment for CIPN available. Among other substances, oxaliplatin causes CIPN in up to 80% of treated patients. Here,...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Hohmann, Stephan W., Angioni, Carlo, Tunaru, Sorin, Lee, Seungkyu, Woolf, Clifford J., Offermanns, Stefan, Geisslinger, Gerd, Scholich, Klaus, Sisignano, Marco
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5428564/
https://ncbi.nlm.nih.gov/pubmed/28348394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00591-0
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