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A Global Approach for Quantitative Super Resolution and Electron Microscopy on Cryo and Epoxy Sections Using Self-labeling Protein Tags

Correlative light and electron microscopy (CLEM) is a powerful approach to investigate the molecular ultrastructure of labeled cell compartments. However, quantitative CLEM studies are rare, mainly due to small sample sizes and the sensitivity of fluorescent proteins to strong fixatives and contrast...

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Müller, Andreas, Neukam, Martin, Ivanova, Anna, Sönmez, Anke, Münster, Carla, Kretschmar, Susanne, Kalaidzidis, Yannis, Kurth, Thomas, Verbavatz, Jean-Marc, Solimena, Michele
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5428382/
https://ncbi.nlm.nih.gov/pubmed/28154417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00033-x
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