Accelerated disease progression and robust innate host response in aged SIVmac239-infected Chinese rhesus macaques is associated with enhanced immunosenescence

The elderly population infected with HIV-1 is often characterized by the rapid AIDS progression and poor treatment outcome, possibly because of immunosenescence resulting from both HIV infection and aging. However, this hypothesis remains to be fully tested. Here, we studied 6 young and 12 old Chine...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Zheng, Hong-Yi, Zhang, Ming-Xu, Chen, Min, Jiang, Jin, Song, Jia-Hao, Lian, Xiao-Dong, Tian, Ren-Rong, Zhang, Xiao-Liang, Zhang, Lin-Tao, Pang, Wei, Zhang, Gao-Hong, Zheng, Yong-Tang
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2017
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5428349/
https://ncbi.nlm.nih.gov/pubmed/28232735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00084-0
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