Accelerated disease progression and robust innate host response in aged SIVmac239-infected Chinese rhesus macaques is associated with enhanced immunosenescence

The elderly population infected with HIV-1 is often characterized by the rapid AIDS progression and poor treatment outcome, possibly because of immunosenescence resulting from both HIV infection and aging. However, this hypothesis remains to be fully tested. Here, we studied 6 young and 12 old Chine...

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Vydáno v:Sci Rep
Hlavní autoři: Zheng, Hong-Yi, Zhang, Ming-Xu, Chen, Min, Jiang, Jin, Song, Jia-Hao, Lian, Xiao-Dong, Tian, Ren-Rong, Zhang, Xiao-Liang, Zhang, Lin-Tao, Pang, Wei, Zhang, Gao-Hong, Zheng, Yong-Tang
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5428349/
https://ncbi.nlm.nih.gov/pubmed/28232735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00084-0
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