Accelerated disease progression and robust innate host response in aged SIVmac239-infected Chinese rhesus macaques is associated with enhanced immunosenescence

The elderly population infected with HIV-1 is often characterized by the rapid AIDS progression and poor treatment outcome, possibly because of immunosenescence resulting from both HIV infection and aging. However, this hypothesis remains to be fully tested. Here, we studied 6 young and 12 old Chine...

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Zheng, Hong-Yi, Zhang, Ming-Xu, Chen, Min, Jiang, Jin, Song, Jia-Hao, Lian, Xiao-Dong, Tian, Ren-Rong, Zhang, Xiao-Liang, Zhang, Lin-Tao, Pang, Wei, Zhang, Gao-Hong, Zheng, Yong-Tang
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2017
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5428349/
https://ncbi.nlm.nih.gov/pubmed/28232735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00084-0
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