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Therapeutic efficacy and safety of PCSK9-monoclonal antibodies on familial hypercholesterolemia and statin-intolerant patients: A meta-analysis of 15 randomized controlled trials

Proprotein convertase subtilisin/kexin9 monoclonal antibodies (PCSK9-mAb) have been studied intensively to identify their effect in lowering levels of low density lipoprotein cholesterol (LDL-C). However, the applicable target of PCSK9-mAbs remains inconclusive so far. Therefore, this first meta-ana...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Qian, Li Jun, Gao, Yao, Zhang, Yan Mei, Chu, Ming, Yao, Jing, Xu, Di
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5428249/
https://ncbi.nlm.nih.gov/pubmed/28331223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00316-3
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