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PCSK9 Antibodies for the Treatment of Hypercholesterolemia
The serine protease proprotein convertase subtilisin/kexin type 9 (PCSK9) binds to the low-density lipoprotein (LDL) receptor (LDLR) and directs it to lysosomes for intracellular degradation. This results in decreased numbers of LDLR available on the hepatic cell surface to bind LDL particles and re...
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| Publicado no: | Nutrients |
|---|---|
| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4276981/ https://ncbi.nlm.nih.gov/pubmed/25470376 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nu6125517 |
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