Efficacy and Safety of Bempedoic Acid in Patients With Hypercholesterolemia and Statin Intolerance

BACKGROUND: Inability to tolerate statins because of muscle symptoms contributes to uncontrolled cholesterol levels and insufficient cardiovascular risk reduction. Bempedoic acid, a prodrug that is activated by a hepatic enzyme not present in skeletal muscle, inhibits ATP‐citrate lyase, an enzyme up...

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Detalhes bibliográficos
Publicado no:J Am Heart Assoc
Main Authors: Laufs, Ulrich, Banach, Maciej, Mancini, G. B. John, Gaudet, Daniel, Bloedon, LeAnne T., Sterling, Lulu Ren, Kelly, Stephanie, Stroes, Erik S. G.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6509724/
https://ncbi.nlm.nih.gov/pubmed/30922146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.118.011662
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