Remote control of glucose homeostasis in vivo using photopharmacology

Photopharmacology describes the use of light to precisely deliver drug activity in space and time. Such approaches promise to improve drug specificity by reducing off-target effects. As a proof-of-concept, we have subjected the fourth generation photoswitchable sulfonylurea JB253 to comprehensive to...

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Publicat a:Sci Rep
Autors principals: Mehta, Zenobia B., Johnston, Natalie R., Nguyen-Tu, Marie-Sophie, Broichhagen, Johannes, Schultz, Peter, Larner, Dean P., Leclerc, Isabelle, Trauner, Dirk, Rutter, Guy A., Hodson, David J.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5428208/
https://ncbi.nlm.nih.gov/pubmed/28331198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00397-0
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