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Allosteric Optical Control of a Class B G‐Protein‐Coupled Receptor
Allosteric regulation promises to open up new therapeutic avenues by increasing drug specificity at G‐protein‐coupled receptors (GPCRs). However, drug discovery efforts are at present hampered by an inability to precisely control the allosteric site. Herein, we describe the design, synthesis, and te...
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| Publicado no: | Angew Chem Int Ed Engl |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5031193/ https://ncbi.nlm.nih.gov/pubmed/27059784 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201600957 |
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