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Whole-exome sequencing identifies a novel de novo mutation in DYNC1H1 in epileptic encephalopathies

Epileptic encephalopathies (EE) are a group of severe childhood epilepsy disorders characterized by intractable seizures, cognitive impairment and neurological deficits. Recent whole-exome sequencing (WES) studies have implicated significant contribution of de novo mutations to EE. In this study, we...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Lin, Zhongdong, Liu, Zhenwei, Li, Xiucui, Li, Feng, Hu, Ying, Chen, Bingyu, Wang, Zhen, Liu, Yong
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5428060/
https://ncbi.nlm.nih.gov/pubmed/28325891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00208-6
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