Targeting to the non-genomic activity of retinoic acid receptor-gamma by acacetin in hepatocellular carcinoma

We recently demonstrated that retinoic acid receptor-γ (RARγ) is overexpressed and acts as a tumor promoter in hepatocellular carcinoma (HCC). The oncogenic activity of RARγ is mainly attributed to its physiological interaction with p85α regulatory subunit of PI3K leading to constitutive activation...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Zeng, Wenjun, Zhang, Chunyun, Cheng, Hongwei, Wu, Yun-Long, Liu, Jie, Chen, Zekun, Huang, Jian-gang, Ericksen, Russell Erick, Chen, Liqun, Zhang, Haiping, Wong, Alice Sze Tsai, Zhang, Xiao-kun, Han, Weiping, Zeng, Jin-Zhang
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2017
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5428017/
https://ncbi.nlm.nih.gov/pubmed/28336971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00233-5
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires