Mass-spectrometric analysis of agonist-induced retinoic acid receptor gamma conformational change.

Apo and holo forms of retinoic acid receptors, and other nuclear receptors, display differential sensitivity to proteolytic digestion that likely reflects the distinct conformational states of the free and liganded forms of the receptor. We have developed a method for rapid peptide mapping of holo-r...

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Dettagli Bibliografici
Autori principali: Peterson, Valerie J, Barofsky, Elisabeth, Deinzer, Max L, Dawson, Marcia I, Feng, Kai-Chia, Zhang, Xiao-kun, Madduru, Machender R, Leid, Mark
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2002
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1222374/
https://ncbi.nlm.nih.gov/pubmed/11829754
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