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Mass-spectrometric analysis of agonist-induced retinoic acid receptor gamma conformational change.

Apo and holo forms of retinoic acid receptors, and other nuclear receptors, display differential sensitivity to proteolytic digestion that likely reflects the distinct conformational states of the free and liganded forms of the receptor. We have developed a method for rapid peptide mapping of holo-r...

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Main Authors: Peterson, Valerie J, Barofsky, Elisabeth, Deinzer, Max L, Dawson, Marcia I, Feng, Kai-Chia, Zhang, Xiao-kun, Madduru, Machender R, Leid, Mark
Formato: Artigo
Idioma:Inglês
Publicado: 2002
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1222374/
https://ncbi.nlm.nih.gov/pubmed/11829754
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