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Markov modeling reveals novel intracellular modulation of the human TREK-2 selectivity filter
Two-pore domain potassium (K2P) channel ion conductance is regulated by diverse stimuli that directly or indirectly gate the channel selectivity filter (SF). Recent crystal structures for the TREK-2 member of the K2P family reveal distinct “up” and “down” states assumed during activation via mechani...
Uloženo v:
| Vydáno v: | Sci Rep |
|---|---|
| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group UK
2017
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5428000/ https://ncbi.nlm.nih.gov/pubmed/28377596 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00256-y |
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