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The dynamic interacting landscape of MAPL reveals essential functions for SUMOylation in innate immunity
Activation of the innate immune response triggered by dsRNA viruses occurs through the assembly of the Mitochondrial Anti-Viral Signaling (MAVS) complex. Upon recognition of viral dsRNA, the cytosolic receptor RIG-I is activated and recruited to MAVS to activate the immune signaling response. We her...
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| 出版年: | Sci Rep |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5427825/ https://ncbi.nlm.nih.gov/pubmed/28273895 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00151-6 |
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