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The dynamic interacting landscape of MAPL reveals essential functions for SUMOylation in innate immunity
Activation of the innate immune response triggered by dsRNA viruses occurs through the assembly of the Mitochondrial Anti-Viral Signaling (MAVS) complex. Upon recognition of viral dsRNA, the cytosolic receptor RIG-I is activated and recruited to MAVS to activate the immune signaling response. We her...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5427825/ https://ncbi.nlm.nih.gov/pubmed/28273895 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00151-6 |
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