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Watasemycin biosynthesis in Streptomyces venezuelae: thiazoline C-methylation by a type B radical-SAM methylase homologue

2-Hydroxyphenylthiazolines are a family of iron-chelating nonribosomal peptide natural products that function as virulence-conferring siderophores in various Gram-negative bacteria. They have also been reported as metabolites of Gram-positive Streptomyces species. Transcriptional analyses of Strepto...

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Detalles Bibliográficos
Publicado en:Chem Sci
Main Authors: Inahashi, Yuki, Zhou, Shanshan, Bibb, Maureen J., Song, Lijiang, Al-Bassam, Mahmoud M., Bibb, Mervyn J., Challis, Gregory L.
Formato: Artigo
Idioma:Inglês
Publicado: Royal Society of Chemistry 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5427693/
https://ncbi.nlm.nih.gov/pubmed/28553520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6sc03533g
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