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Functional Analysis of relA and rshA, Two relA/spoT Homologues of Streptomyces coelicolor A3(2)

Deletion of the (p)ppGpp synthetase gene, relA, of Streptomyces coelicolor A3(2) results in loss of production of the antibiotics actinorhodin (Act) and undecylprodigiosin (Red) and delayed morphological differentiation when the mutant is grown under conditions of nitrogen limitation. To analyze the...

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Autors principals: Sun, Jongho, Hesketh, Andrew, Bibb, Mervyn
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC99647/
https://ncbi.nlm.nih.gov/pubmed/11344157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.183.11.3488-3498.2001
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