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Functional Analysis of relA and rshA, Two relA/spoT Homologues of Streptomyces coelicolor A3(2)

Deletion of the (p)ppGpp synthetase gene, relA, of Streptomyces coelicolor A3(2) results in loss of production of the antibiotics actinorhodin (Act) and undecylprodigiosin (Red) and delayed morphological differentiation when the mutant is grown under conditions of nitrogen limitation. To analyze the...

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Detalhes bibliográficos
Main Authors: Sun, Jongho, Hesketh, Andrew, Bibb, Mervyn
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC99647/
https://ncbi.nlm.nih.gov/pubmed/11344157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.183.11.3488-3498.2001
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